Delirium Bibliography

**The Delirium Bibliography is moving!**

 

We're excited to announce that the Delirium Bibliography has been moved to the Network for Investigation of Delirium: Unifying Scientists (NIDUS) website! The new bibliography includes well over 3,000 references on delirium and acute care for elders in addition to new references on pediatric delirium, as well. Articles in the new bibliography are still indexed by keywords taken from MEDLINE and other relevant databases, and they can be easily browsed with a search function. Questions? Email margaretwebb@hsl.harvard.edu

The searchable delirium bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons.  The HELP team keeps it updated for you on a monthly basis!  Feel free to search by author, title, keywords. It is primarily intended for clinicians and researchers interested in exploring these topics.

Each article is indexed by keywords taken from MEDLINE and other relevant databases.

You may base your search on as many search terms as you like. A search term can be a keyword, an author's name, all or part of an article's title, or any word or phrase that you might expect to find in an article's abstract. You may then indicate whether you would like to limit the search to one or more options.

The results are prioritized so that entries including all search terms will be listed first, but you can indicate whether to then sort by title (the default), by author, by journal name or by publication year.

You may further restrict to a topic category. Note: If you do not enter any search terms, the results will include all of the entries for the selected topic category.

More information about each entry on this page is available by moving the mouse over the green information symbols.

Please note that Pub Med Central (PMC) full text links are provided wherever available.  However, due to copyright restrictions, only abstracts can be provided for articles not available in PMC.

Total Results: 3263

  • The impact of delirium in the intensive care unit on hospital length of stay. 2001 Ely EW, Gautam S, Margolin R, Francis J, May L, Speroff T, Truman B, Dittus R, Bernard R, Inouye SK. Intensive care medicine, 27:12 (1892-900)
    • Title

      The impact of delirium in the intensive care unit on hospital length of stay.

    • Authors
      Ely EW, Gautam S, Margolin R, Francis J, May L, Speroff T, Truman B, Dittus R, Bernard R, Inouye SK
    • Year
      2001
    • Journal
      Intensive care medicine
    • URL
    • Abstract
      To determine the relationship between delirium in the intensive care unit (ICU) and outcomes including length of stay in the hospital.
    • PubMed ID
  • What does the medical record reveal about functional status? A comparison of medical record and interview data. 2001 Bogardus ST, Towle V, Williams CS, Desai MM, Inouye SK. Journal of general internal medicine, 16:11 (728-36)
    • Title

      What does the medical record reveal about functional status? A comparison of medical record and interview data.

    • Authors
      Bogardus ST, Towle V, Williams CS, Desai MM, Inouye SK
    • Year
      2001
    • Journal
      Journal of general internal medicine
    • URL
    • Abstract
      Functional status measures are potent independent predictors of hospital outcomes and mortality. The study objective was to compare medical record with interview data for functional status.
    • PubMed ID
  • An algorithm for prospective individual matching in a non-randomized clinical trial. 2001 Charpentier PA, Bogardus ST, Inouye SK. Journal of clinical epidemiology, 54:11 (1166-73)
    • Title

      An algorithm for prospective individual matching in a non-randomized clinical trial.

    • Authors
      Charpentier PA, Bogardus ST, Inouye SK
    • Year
      2001
    • Journal
      Journal of clinical epidemiology
    • URL
    • Abstract
      A method is described to achieve balance across prognostic factors in intervention trials for which randomized allocation to treatment group is not possible. The method involves prospective individual matching of patients that have already been assigned to treatment groups. Data can be analyzed using methods appropriate for prospective matched cohort studies. Successful implementation depends on the number and complexity of factors to be matched, and on the number of available control patients. Simulation studies suggest that, in order to yield satisfactory match rates and to reduce costs associated with screening unmatched controls, no more than three prognostic factors should generally be considered. Baseline prognostic indices, incorporating information from multiple variables, provide effective matching factors. The implementation of the method in a successful clinical trial, the Delirium Prevention Trial, is discussed. In that study, treatment group was determined by hospital admission to either an intervention floor or to one of two usual care hospital floors. The ratio of available control to intervention patients was 1.3, and 95% of the eligible intervention floor patients were successfully matched to control floor patients. Excellent balance was demonstrated for non-matching factors, due in part to the use of a composite baseline risk score as a matching factor. In addition, external validity is enhanced because most eligible intervention patients are enrolled as they present. The methods outlined in this report provide a methodologically rigorous alternative for achieving balance across treatment groups, with respect to important prognostic factors, in non-randomized clinical trials, and will have broad applicability in the numerous situations in which randomization is not possible.
    • PubMed ID
  • Dementia and race: are there differences between African Americans and Caucasians? 2001 Froehlich TE, Bogardus ST, Inouye SK. Journal of the American Geriatrics Society, 49:4 (477-84)
    • Title

      Dementia and race: are there differences between African Americans and Caucasians?

    • Authors
      Froehlich TE, Bogardus ST, Inouye SK
    • Year
      2001
    • Journal
      Journal of the American Geriatrics Society
    • URL
    • Abstract
      This study provides an overview of racial differences in etiology and prevalence of dementia. Preliminary findings indicate that the clinical and molecular etiologies of dementia differ between races. African Americans have a higher prevalence of vascular dementia and a lower prevalence of Parkinsonian dementia than do Caucasians. The genetic etiologies of Alzheimer's-type dementia appear to differ between African Americans and Caucasians. The variations in dementia etiologies and in cognitive testing accuracy between races suggests the urgent need to develop racially appropriate cognitive assessment methods and to develop preventive and treatment etiologies differently according to racial background of individual patients.
    • PubMed ID
  • Risk adjustment for older hospitalized persons: a comparison of two methods of data collection for the Charlson index. 2001 van Doorn C, Bogardus ST, Williams CS, Concato J, Towle VR, Inouye SK. Journal of clinical epidemiology, 54:7 (694-701)
    • Title

      Risk adjustment for older hospitalized persons: a comparison of two methods of data collection for the Charlson index.

    • Authors
      van Doorn C, Bogardus ST, Williams CS, Concato J, Towle VR, Inouye SK
    • Year
      2001
    • Journal
      Journal of clinical epidemiology
    • URL
    • Abstract
      To compare Charlson indices based on chart data and ICD-9 data for agreement overall and on rating specific comorbid conditions, and to compare mortality risks associated with these indices. Prospective cohort study. Six general medicine wards at Yale-New Haven Hospital. 524 consecutive patients who had no clinical evidence of delirium at enrollment, admitted between November 6, 1989 and July 31, 1991, aged 70 years or older. Death within 1 year of the index hospital admission date. Scores using the chart-based data were significantly higher than those using ICD-9 data. About half of the individual conditions showed fair-to-good agreement between the two scores, whereas the other half showed poor agreement. A comparison of mortality prediction indicated that the weightings assigned to individual comorbidities differed substantially from those used in Charlson's original index. While mortality prediction of each individual index was comparable, the ICD-9 and chart indices contributed independently to mortality prediction in the presence of the other. Low agreement between Charlson scores based on the two methods of data collection and their cumulative contribution to mortality prediction suggest that these indices may include different information. Our results suggest that the original Charlson index may not provide optimal risk adjustment for elderly general medicine samples. We suggest development of an empirically-derived index of comorbid conditions and weights may be warranted for older general medical patients.
    • PubMed ID
  • Cognitive and other adverse effects of diphenhydramine use in hospitalized older patients. 2001 Agostini JV, Leo-Summers LS, Inouye SK. Archives of internal medicine, 161:17 (2091-7)
    • Title

      Cognitive and other adverse effects of diphenhydramine use in hospitalized older patients.

    • Authors
      Agostini JV, Leo-Summers LS, Inouye SK
    • Year
      2001
    • Journal
      Archives of internal medicine
    • URL
    • Abstract
      Diphenhydramine hydrochloride is a commonly prescribed medicine in hospitalized patients, but its adverse effects on older patients remain unclear.
    • PubMed ID
  • Acute confusional state in elderly orthopaedic patients: factors of importance for detection in nursing care. 2001 Andersson EM, Gustafson L, Hallberg IR. International journal of geriatric psychiatry, 16:1 (7-17)
    • Title

      Acute confusional state in elderly orthopaedic patients: factors of importance for detection in nursing care.

    • Authors
      Andersson EM, Gustafson L, Hallberg IR
    • Year
      2001
    • Journal
      International journal of geriatric psychiatry
    • URL
    • Abstract
      The aims of this study were to identify factors of significance in the development of acute confusional state (ACS) and the differences between patients who developed ACS and those who did not.
    • PubMed ID
  • Methodologic issues in conducting research on hospitalized older people. 2001 Berkman CS, Leipzig RM, Greenberg SA, Inouye SK. Journal of the American Geriatrics Society, 49:2 (172-8)
    • Title

      Methodologic issues in conducting research on hospitalized older people.

    • Authors
      Berkman CS, Leipzig RM, Greenberg SA, Inouye SK
    • Year
      2001
    • Journal
      Journal of the American Geriatrics Society
    • URL
    • Abstract
      To describe challenges in conducting research with hospitalized geriatric patients.
    • PubMed ID
  • Goals for the care of frail older adults: do caregivers and clinicians agree? 2001 Bogardus ST, Bradley EH, Williams CS, Maciejewski PK, van Doorn C, Inouye SK. The American journal of medicine, 110:2 (97-102)
    • Title

      Goals for the care of frail older adults: do caregivers and clinicians agree?

    • Authors
      Bogardus ST, Bradley EH, Williams CS, Maciejewski PK, van Doorn C, Inouye SK
    • Year
      2001
    • Journal
      The American journal of medicine
    • URL
    • Abstract
      Establishing shared treatment goals for patients may improve the quality of care by facilitating achievement of appropriate and desired outcomes. The purpose of this study was to describe types of family caregiver and physician treatment goals for frail elderly patients who had a high prevalence of cognitive impairment, and to ascertain the level of agreement between family caregivers and physicians on principal treatment goals.
    • PubMed ID
  • Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). 2001 Ely EW, Inouye SK, Bernard GR, Gordon S, Francis J, May L, Truman B, Speroff T, Gautam S, Margolin R, Hart RP, Dittus R. JAMA : the journal of the American Medical Association, 286:21 (2703-10)
    • Title

      Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU).

    • Authors
      Ely EW, Inouye SK, Bernard GR, Gordon S, Francis J, May L, Truman B, Speroff T, Gautam S, Margolin R, Hart RP, Dittus R
    • Year
      2001
    • Journal
      JAMA : the journal of the American Medical Association
    • URL
    • Abstract
      Delirium is a common problem in the intensive care unit (ICU). Accurate diagnosis is limited by the difficulty of communicating with mechanically ventilated patients and by lack of a validated delirium instrument for use in the ICU.
    • PubMed ID
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